乙草胺对大鼠肝细胞G蛋白偶联受体介导的胞浆钙离子振荡的调控

doi:10.14088/j.cnki.issn0439-8114.2019.16.023

湖北农业科学 ›› 2019, Vol. 58 ›› Issue (16): 104-106.doi: 10.14088/j.cnki.issn0439-8114.2019.16.023

乙草胺对大鼠肝细胞G蛋白偶联受体介导的胞浆钙离子振荡的调控

张彬彬^a, 王玖^b

滨州医学院,a.药学院; b.公共卫生与管理学院,山东烟台 264003

收稿日期:2018-10-18 出版日期:2019-08-25 发布日期:2019-11-12
作者简介:张彬彬（1971-）,女,山东惠民人,副教授,硕士,主要从事动物生理研究,（电话）18553532969（电子信箱）bzzbbwj@126.com。

Regulation of acetochlor on the G-protein-coupled receptors mediated calcium oscillation in rat hepatocytes

ZHANG Bin-bin^a, WANG Jiu^b

a.School of Pharmacy; b.School of Public Health and Management,Binzhou Medical University,Yantai 264003,Shandong,China

Received:2018-10-18 Online:2019-08-25 Published:2019-11-12

摘要/Abstract

摘要： 以大鼠肝细胞为研究对象,研究乙草胺对大鼠肝细胞G蛋白偶联受体介导胞浆钙振荡的调控。结果表明,单独乙草胺刺激不引发胞浆钙离子振荡,乙草胺和PE同时作用对肾上腺素能受体有抑制作用且具有明显的量效反应关系。

关键词: 乙草胺, 肾上腺素能受体, 钙振荡, 肝细胞

Abstract: The effects of different concentrations of acetochlor on the regulation of cytosolic calcium oscillation induced by G protein-coupled receptors in rat hepatocytes was investigated. The results showed that acetochlor and PE could inhibit PE receptors which the effect of acetochlor on it were dose-dependent, and acetochlor alone had no effect on PE receptors.

Key words: acetochlor, adrenergic receptor, calcium oscillations, hepatocytes

中图分类号:

Q2
S482

张彬彬, 王玖. 乙草胺对大鼠肝细胞G蛋白偶联受体介导的胞浆钙离子振荡的调控[J]. 湖北农业科学, 2019, 58(16): 104-106.

ZHANG Bin-bin, WANG Jiu. Regulation of acetochlor on the G-protein-coupled receptors mediated calcium oscillation in rat hepatocytes[J]. HUBEI AGRICULTURAL SCIENCES, 2019, 58(16): 104-106.

乙草胺对大鼠肝细胞G蛋白偶联受体介导的胞浆钙离子振荡的调控

Regulation of acetochlor on the G-protein-coupled receptors mediated calcium oscillation in rat hepatocytes

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