湖北农业科学 ›› 2019, Vol. 58 ›› Issue (22): 149-151.doi: 10.14088/j.cnki.issn0439-8114.2019.22.035

• 畜牧·兽医 • 上一篇    下一篇

中药组方溶宁对急性溶血性贫血小鼠模型外周血及骨髓的影响

王汉海, 曹慧, 隋美霞, 万永霞, 高顺航   

  1. 山东省高校生物化学与分子生物学重点实验室/潍坊学院生物与农业工程学院,山东 潍坊 261061
  • 收稿日期:2019-01-07 出版日期:2019-11-25 发布日期:2019-12-09
  • 通讯作者: 万永霞(1971-),女,山东潍坊人,副教授,硕士,主要从事生物科学方面的教学和研究,(电话)13853678279(电子信箱)wanyx567@126.com。
  • 作者简介:王汉海(1968-),男,山东潍坊人,副教授,硕士,主要从事生物科学方面的教学和研究,(电话)13563681696(电子信箱)hanhaiwang@163.com。
  • 基金资助:
    山东省自然科学基金项目(ZR2017QC009); 潍坊市科技发展计划项目(201002088; 201101024); 潍坊学院大学生研究训练计划项目(WFUSRTP2017L1)

Influences of Chinese drugs rongning preparation on peripheral blood and bone marrow of mice with hemolytic anemia

WANG Han-hai, CAO hui, SUI Mei-xia, WAN Yong-xia, GAO Shun-hang   

  1. Key Laboratory of Biochemistry and Molecular Biology in Universities of Shandong Province/College of Bio-engineering and Agriculture,Weifang University,Weifang 261061,Shandong,China
  • Received:2019-01-07 Online:2019-11-25 Published:2019-12-09

摘要: 建立小鼠急性溶血性贫血模型并观察中药组方溶宁的治疗效果,测定模型小鼠外周血和骨髓组织结构的变化。将32只小鼠随机分为空白对照组、模型组、试验对照组和试验组,连续进行血常规检测以及石蜡切片和超微切片观察。结果表明,中药组方溶宁可改善外周循环血及骨髓细胞的超微结构,对溶血性贫血有一定的防治效果。

关键词: 溶宁, 溶血性贫血, 小鼠, 骨髓

Abstract: To explore the mechanism of effect of Chinese drugs rongning preparation on hemolytic anemia mice by determination of the peripheral blood and bone marrow tissue structure. 32 kunming mice were randomly divided into blank control group, model group, control group and experimental group. The results showed that the rongning preparation can improve the peripheral blood and the ultrastructure of bone marrow cells, and have a precise curative effect on treating preventable hemolytic anemia through paraffin section method and continuous determination of the blood routine.

Key words: rongning, hemolytic anemia, mice, bone marrow

中图分类号: