Research progress of phage arbitrium communication system

doi:10.14088/j.cnki.issn0439-8114.2021.09.001

Abstract

Abstract: During the infection of the host, the temperate bacteriophages can enter lytic or lysogenic life cycles according to the population density. In recent years, for SPbeta phages in Bacillus subtilis infection process, a communication system was found to determine the process of lysis-lysogeney. The communication system is called arbitrium communication system. Arbitrium communication system is composed of three phage genes：aimR,aimP,aimX. The AimR protein encoded by the aimR gene is the key protein of the arbitrium communication system. The arbitrium peptide is transported into the cell to bind with the AimR protein, which releases the regulation effect of the AimR protein on the aimX gene, allowing the bacteriophage to enter the lysogenic cycle. The structural characteristics of AimR and the mechanism of peptide action were reviewed, in order to provide valuable reference information for the in-depth study of this communication system and for disease control by Bacillus subtilis.

Key words: temperate bacteriophages, lysis-lysogeny, arbitrium peptide, AimR

CLC Number:

JIAO Wen-hao, XU Bing-hong, LIU Jing, LIU Pei-yuan, YAN Han-chi. Research progress of phage arbitrium communication system[J]. HUBEI AGRICULTURAL SCIENCES, 2021, 60(9): 5-9.

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