石墨烯功能修饰材料的电化学分析性能研究

doi:10.14088/j.cnki.issn0439-8114.2019.07.001

摘要/Abstract

摘要： 石墨烯（GR）是一种单原子碳纳米材料,具有独特的二维共轭平面结构,表现出优越的化学、力学、热学和电学性能。氧化石墨烯（GO）是制备石墨烯的前驱体,类似于石墨烯的二维结构,GO表面含大量的含氧官能团,具有良好的水溶分散性,GO通过化学还原方法可以得到导电性良好的GR材料。将GR材料与其他功能材料进行复合,可进一步改善复合物的物理和化学性能,如可分散性、可加工性和电催化活性等。综述了GR（包括GO）与碳纳米材料、金属纳米粒子、金属氧化物、非金属单质、聚合物或其他功能生物分子材料结合后,得到复合功能修饰材料用于构建高性能电化学生物传感器。探究了复合制备材料的纳米结构特征、功能结构作用对于提高传感器的电催化和电化学选择性能等方面的应用。

关键词: 石墨烯（GR）, 氧化石墨烯（GO）, 功能修饰, 电化学, 分析性能

Abstract: Graphene （GR）, as a kind of monatomic carbon nanomaterial, which has a unique two-dimensional conjugate planar structure and shows excellent chemical, mechanical, thermal and electrical properties. Graphene oxide （GO） is a precursor of graphene, which similar to the two-dimensional structure of graphene. GO surface containing a large number of oxygen-containing functional groups,resulting has a good water-soluble dispersion. The good conductivity of GR materials can be obtained by the chemical reduction method of GO. The graphene materials compositing with other functional materials would further improve the complex physical and chemical properties, such as dispersibility, workability and electrocatalytic activity. The fabricated high performance electrochemical biosensors by combining graphene （including GO） with carbon nanomaterials, metallic nanoparticles, metal oxides, non-metallic, polymers or other functional biomolecule materials to form the composite functional modified materials were reviewed. The nanostructural features of the composite material were explored and the application of its functional structure for improving the electrocatalytic and electrochemical selectivity of the sensor was also discussed.

Key words: graphene（GR）, graphene oxide（GO）, functional modification, electrochemistry, analysis performance

中图分类号:

TH145.1⁺3

郑德论, 张锐龙, 陈键侨, 王呈文, 陈学武, 张彩云. 石墨烯功能修饰材料的电化学分析性能研究[J]. 湖北农业科学, 2019, 58(7): 5-6.

ZHENG De-lun, ZHANG Rui-long, CHEN Jian-qiao, WANG Cheng-wen, CHEN Xue-wu, ZHANG Cai-yun. Electrochemical analysis performance study of graphene functional modified materials[J]. HUBEI AGRICULTURAL SCIENCES, 2019, 58(7): 5-6.

参考文献

[1] XU J H,WANG Y Z,HU S S.Nanocomposites of graphene and graphene oxides:Synthesis,molecular functionalization and application in electrochemical sensors and biosensors[J].Microchim acta,2017,184:1-44.
[2] GEORGAKILAS V,TIWAR J N,CHRISTIAN KEMP K,et al.Noncovalent functionalization of graphene and graphene oxide for energy materials,biosensing,catalytic,and biomedical applications[J].Chem Rev,2016,116:5464-5519.
[3] AMBROSI A,CHUA C K,BONANNI A,et al.Electrochemistry of graphene and related materials[J].Chem Rev,2014,114(14):7150-7188.
[4] DREYER D R,TODD A D,BIELAWSKI C W.Harnessing the chemistry of graphene oxide[J].Chem Soc Rev,2014,43(15):5288-5301.
[5] BAI S,SHEN X.Graphene-inorganic nanocomposites[J].RSC Adv,2012,2(1):64-98.
[6] ZHAO B T,ZHENG Y,YE F,et al.ACS Appl. Multifunctional iron oxide nanoflake/graphene composites derived from mechanochemical synthesis for enhanced lithium storage and electrocatalysis[J].Mater Interfaces,2015,7:14446-14455.
[7] BUNCH J S,YAISH Y,BRINK M,et al.Coulomb oscillations and hall effect in Quasi-2D graphite quantum dots[J].Nano Lett,2005,5(2):287-290.
[8] REINA A,JIA X,HO J,et al.Large area,few-layer graphene films on arbitrary substrates by chemical vapor deposition[J].Nano Lett,2008,9(1):30-35.
[9] BERGER C,SONG Z,LI X,et al.Electronic confinement and coherence in patterned epitaxial graphene[J].Science,2006,312(5777):1191-1196.
[10] GUO H L,WANG X F,QIAN Q Y,et al.A green approach to the synthesis of graphene nanosheets[J].ACS Nano,2009, 3(9):2653-2659.
[11] GIOVANNI M,BONANNI A,PUMERA M.Detection of DNA hybridization on chemically modified graphene platforms[J].Analyst,2012,137(3):580-583.
[12] CHEN D,FENG H,LI J.Graphene oxide:preparation,functionalization,and electrochemical applications[J].Chem Rev,2012112(11):6027-6053.
[13] PAREDES J I,VILLAR-RODIL S,FERNáNDEZ-MERINO M J,et al. Environmentally friend-ly approaches toward the mass production of processable graphene from graphite oxide[J].J Mater Chem,2011,21(2):298-306.
[14] SI Y C,SAMULSKI E T.Synthesis of water soluble graphene[J].Nano Lett,2008,8(6):1679-1682.
[15] SONG J,QIAO J,SHUANG S,et al.Synthesis of neutral red covalently functionalized graphene nanocomposite and the electrocatalytic properties toward uric acid[J].J Mater Chem,2012,22(2):602-608.
[16] LUO J H,LI B L,LI N B,et al.Sensitive detection of gallic acid based on polyethyleneimine-functionalized graphene modified glassy carbon electrode[J].Sensors actuators B chem,2013,186:84-89.
[17] GUO S,WEN D,ZHAI Y,et al.Platinum nanoparticle ensemble-on-graphene hybrid nanosheet one-pot rapid synthesis and used as new electrode material for electrochemical sensing[J].ACS Nano,2010,4(7):3959-3968.
[18] WANG Y,XIAO Y,MA X,et al.Label-free and sensitive thrombin sensing on a molecularly grafted aptamer on graphene[J].Chem Commun(Camb),2012,48(5):738-740.
[19] FAN Z,LIU B,LIU X,et al.A flexible and disposable hybrid electrode based on Cu nanowires modified graphene transparent electrode for non-enzymatic glu-cose sensor[J].Electrochim acta,2013,109:602-608.
[20] GEORGAKILAS V,OTYEPKA M,BOURLINOS A B,et al.Functionalization of graphene:covalent and non-covalent approaches,derivatives and applications[J].Chem Rev,2012,112(11):6156-6214.
[21] ZHU Y,JAMES D K,TOUR J M,et al.New routes to graphene,graphene oxide and their related applications[J].Adv Mater,2012,24(36):4924-4955.
[22] KOCHMANN S,HIRSCH T,WOLFBEIS O S,et al.Graphenes in chemical sensors and biosensors.TrAC[J].Trends Anal Chem,2012,39:87-113.
[23] FILIP J,KASáK P,TKAC J. Graphene as signal amplifier for preparation of ultrasensitive electrochemical biosensors[J].Chemical papers,2015,69(1):112-133.
[24] YANG F,HE D H,ZHENG B Z,et al.Self-assembled hybrids with xanthate functionalized carbon nanotubes and electro-exfoliating graphene sheets for electrochemical sensing of copper ions[J].J Electroanal Chem,2016,767:100-107.
[25] REN S Y,JI H F,ZHANG Z H.Fabrication of sensitive layers of the 3D graphene electrochemical biosensor for heavy metal ions detection[J].Journal of light industry,2016,31(3): 14-20.
[26] DALK₁RAN B,ERDEN P E,K₁L₁ÇE. Electrochemical biosensing of galactose based on carbon materials:graphene versus multi-walled carbon nanotubes[J].Anal Bioanal Chem,2016,408:4329-4339.
[27] ZHAN F P,GAO F,WANG X,et al.Determination of lead(II) by adsorptive stripping voltammetry using a glassy carbon electrode modified with β-cyclodextrin and chemically reduced graphene oxide composite[J].Microchimica acta,2016,183(3):1169-1176.
[28] WANG C,SUN Y L,YU X H,et al.Ag-Pt hollow nanoparticles anchored reduced graphene oxidecomposites for non-enzymatic glucose biosensor[J].J Mater Sci:Mater Electron,2016,27(9):9370-9378.
[29] KRISHNA R,CAMPIÑA J M,PAULA M V,et al. Reduced graphene oxide-nickel nanoparticles/biopolymer compositefilms for the sub-millimolar detection of glucose[J].Analyst,2016, 141:4151-4161.
[30] REN S,WANG H,ZHANG Y F,et al.Convenient and controllable preparation of anovel uniformly nitrogen doped porous graphene/Pt nanoflower material and its highly-efficient electrochemical biosensing[J].Analyst,2016,141:2741-2747.
[31] ZHOU Y Q,CAO J,ZHAO J,et al.Temperature-responsive amperometric H₂O₂ biosensor using a composite film consisting of poly(N-isopropylacrylamide)-b-poly(2-acrylamidoethyl benzoate),grapheneoxide and hemoglobin[J].Microchim Acta,2016,183:2501-2508.
[32] MANI V,DINESH B,CHEN S M,et al.Direct electrochemistry of myoglobin at reduced graphene oxide-multiwalled carbon nanotubes-platinum nanoparticles nanocomposite and biosensing towards hydrogen peroxide and nitrite[J].Biosensors bioelectronics,2014,53(15):420-427.
[33] YOLA M L,EREN T,ATAR N.A novel and sensitive electrochemical DNA biosensor based on Fe@Au nanoparticles decorated graphene oxide[J].Electrochim Acta,2014,125:38-47.
[34] HUANG H Y,BAI W Q,DONG C X,et al.An ultrasensitive electrochemical DNA biosensorbased on graphene/Au nanorod/polythionine for human papillomavirus DNA detection[J].Biosensors bioelectronics,2015,68(15):442-446.
[35] ZHANG J J,CHEN S H,RUO Y,et al.An ultrasensitive electrochemiluminescent biosensorfor the detection of concanavalin A based on poly(ethylenimine)reduced graphene oxide and hollow gold nanoparticles[J].Anal Bioanal Chem,2015,407:447-453.
[36] JENITA R G,BABU J K,KUMAR G G,et al.Watsonia meriana flower like Fe3O4/reduced graphene oxidenanocomposite for the highly sensitive and selective electrochemicalsensing of dopamine[J].J Alloys Compd,2016,688:500-512.
[37] CHEN X Q,YAN H Q,SHI Z F,et al.A novel biosensor based on electro-co-deposition of sodium alginate-Fe₃O₄-graphene compositeon the carbon ionic liquid electrode for the directelectrochemistry and electrocatalysis of myoglobin[J].Polym Bull,2017,74:75-90.
[38] PENG D L,JI H F,DONG X D,et al.Highly sensitive electrochemical bioassay for Hg(II) detection based on plasma-polymerized propargylamineand three-dimensional reduced graphene oxide nanocomposite[J].Plasma Chem Plasma Process,2016,36:1051-1065.
[39] ZHUO B G,LI Y Q, ZHANG A, et al.An electrochemiluminescence biosensor forsensitive and selective detection of Hg²+ based on interaction between nucleotides andferrocene-graphene nanosheets[J].J Mater Chem B,2014,2:3263-3270.
[40] LIU J Q,KONG N,LI A H,et al.Graphene bridged enzyme electrodes for glucose biosensing application[J].Analyst,2013, 138:2567-2575.
[41] LING Y Y,HUANG Q A,ZHU M S,et al.A facile one-step electrochemical fabrication of reduced graphene oxide-mutilwall carbon nanotubes-phospotungstic acid composite for dopamine sensing[J].Electroanal Chem,2013,693:9-15.
[42] DONG X C,WANG X W,WANG L H,et al.3D Graphene foam as a monolithic and macroporous carbon electrode for electrochemical sensing[J].ACS Appl Mater Interfaces,2012,4(6):3129-3133.
[43] 于小雯,盛凯旋,陈骥,等.基于石墨烯修饰电极的电化学生物传感[J].化学学报,2014,72(3):319-332.
[44] MELDE B J,JOHNSON B J.Mesoporous materials in sensing:morphology and functionality at the meso-interface[J].Anal. Bioanal Chem,2010,398:1565-1573.
[45] ZENG G H,XING Y B,GAO J,et al.Unconventional layer-by-layer assembly of graphene multilayer films for enzyme-based glucose and maltose biosensing[J].Langmuir,2010,26(18):15022-15026.