湖北农业科学 ›› 2026, Vol. 65 ›› Issue (6): 133-139.doi: 10.14088/j.cnki.issn0439-8114.2026.06.022

• 药用植物 • 上一篇    下一篇

人工智能结合高效液相色谱指纹图谱在五指毛桃鉴别中的应用

李虹琴1, 刘明川2, 王飞飞3, 刘锐1   

  1. 1.云南云科特色植物检测有限公司,昆明 650106;
    2.云南特色植物提取实验室有限公司,昆明 650106;
    3.云南贝泰妮生物科技集团股份有限公司,昆明 650106
  • 收稿日期:2026-02-13 出版日期:2026-06-25 发布日期:2026-06-26
  • 通讯作者: 刘锐,男,副高级工程师,主要从事食品质量安全的工作,(电子信箱)liurui02@botanee.com。
  • 作者简介:李虹琴(1995-),女,云南昆明人,工程师,主要从事食品检测的工作,(电子信箱)lihongqin@botanee.com。
  • 基金资助:
    云南特色植物提取实验室自主研究项目基金项目(2023YKZY001; 2025YKZY003)

Application of AI combined with high-performance liquid chromatography fingerprint in the identification of Radix Fici Hirtae

LI Hong-qin1, LIU Ming-chuan2, WANG Fei-fei3, LIU Rui1   

  1. 1. Yunnan Yunke Characteristic Plant Testing Co., Ltd., Kunming 650106, China;
    2. Yunnan Characteristic Plant Extraction Laboratory Co., Ltd., Kunming 650106, China;
    3. Yunnan Botanee Bio-technology Group Co., Ltd., Kunming 650106, China
  • Received:2026-02-13 Published:2026-06-25 Online:2026-06-26

摘要: 为了解决五指毛桃(Radix Fici Hirtae)市场上混淆品层出不穷、传统鉴别方法主观性强且依赖经验的问题,结合高效液相色谱(HPLC)指纹图谱与人工智能(AI)技术,收集了五指毛桃样本及混淆品,建立其高效液相色谱指纹图谱,并将改进的YOLO11算法引入中药指纹图谱分析,使其能够自动、精准地识别特征色谱峰,并学习其多维形态学特征,从而建立起从原始图谱到真伪判别的端到端智能鉴别模型。结果表明,构建的YOLO11鉴别模型切实可行,准确率达99.19%,召回率达100.00%,精确率98.25%,特异度98.53%,F1分数99.12%,表明模型在精确性与全面性上达到最佳平衡,能够准确鉴别五指毛桃与非五指毛桃。

关键词: 高效液相色谱指纹图谱, 五指毛桃(Radix Fici Hirtae), 人工智能, YOLO11, 鉴别

Abstract: To address the issues of the continuous emergence of adulterants in the Radix Fici Hirtae market and the subjectivity and experience dependence of traditional identification methods, high-performance liquid chromatography (HPLC) fingerprinting was combined with artificial intelligence (AI) technology. Samples of Radix Fici Hirtae and its adulterants were collected, and their HPLC fingerprints were established. An improved YOLO11 algorithm was introduced into the analysis of traditional Chinese medicine fingerprints, enabling automatic and accurate recognition of characteristic chromatographic peaks and learning of their multi-dimensional morphological features. Consequently, an end-to-end intelligent identification model was established, ranging from raw chromatograms to authenticity discrimination. The results demonstrated that the constructed YOLO11 identification model was feasible, achieving an accuracy of 99.19%, recall of 100.00%, precision of 98.25%, specificity of 98.53%, and an F1 score of 99.12%. These metrics indicated that the model achieved an optimal balance between precision and comprehensiveness, and could accurately distinguish Radix Fici Hirtae from non-Radix Fici Hirtae samples.

Key words: high-performance liquid chromatography fingerprint, Radix Fici Hirtae, artificial intelligence, YOLO11, identification

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