GC-MS/MRM determination of N-Nitrosodimethylamine（NDMA） in Drinking water

doi:10.14088/j.cnki.issn0439-8114.2018.07.025

Abstract

Abstract: A analytical method was developed for determination on N-nitrosodimethylamine by GC-MS/MRM. The determination of NDMA in drinking water by gas chromatography-mass spectrometry/MRM method was established by the optimization of chromatographic column,scanning mode,extraction solvent,pH and concentration method. Linear relationship between the peak area and concentration of NDMA was obtained in the range of 0.05~1.0 mg/L. The detection limit was 0.01 μg/L（S/N=3）.Tests for recovery and precision of this method were 66.93%~85.32% and the relative standard deviation（RSD） was 2.93%~4.19% by adding 2 different concentrations. The method has high sensitivity,wide linear range and optimized the detection conditions of NDMA in drinking water,and it is suitable for the detection of NDMA in drinking water.

Key words: drinking water, N-nitro sodimethylamine（NDMA）, GC-MS/MRM

CLC Number:

O657

ZHAO Li, SHI Zhen, HONG Xue-hua, LI Wen-ting, ZHANG Rui-yu. GC-MS/MRM determination of N-Nitrosodimethylamine（NDMA） in Drinking water[J]. HUBEI AGRICULTURAL SCIENCES, 2018, 57(7): 108-110.

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