Research progress on the toxicity of florfenicol

doi:10.14088/j.cnki.issn0439-8114.2020.12.002

Abstract

Abstract: Florfenicol is a synthetic broad-spectrum antimicrobial derivative of chloramphenicol. It has a wide antibacterial spectrum and has been used to prevent and control respiratory and digestive diseases in pigs. In clinical application, florfenicol may show various toxic reactions at inappropriate or high dose levels, causing varying degrees of damage to animal digestion, reproductive system and different internal organs. The research progress on general toxicity, special toxicity, ecotoxicity and chronotoxicology of florfenicol was reviewed in order to summarize the toxicity characteristics of florfenicol and provide better guidance for clinical use.

Key words: florfenicol, antibacterial drugs, general toxicity, special toxicity, ecotoxicity, chronotoxicology

CLC Number:

S859.8

SUN Ji-chao, DONG Zhen, ZHANG Ji-yu, ZHOU Xu-zheng. Research progress on the toxicity of florfenicol[J]. HUBEI AGRICULTURAL SCIENCES, 2020, 59(12): 9-12.

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