Association analysis between BMP4, Krt85, and PPARGC1A gene polymorphism and meat quality traits in Small Tail Han sheep

doi:10.14088/j.cnki.issn0439-8114.2026.02.024

Abstract

Abstract: InDel polymorphism was used to analyze the four polymorphic sites of the three candidate genes of BMP4, Krt85 and PPARGC1A genes (including drip loss, shear force, moisture, cooking loss, color, crude protein, and crude fat), so as to provide some scientific basis for improving the meat quality of the Small Tail Han sheep. The results showed that: ① polymorphisms in the four sites of the three genes were detected, and all four polymorphic sites had genotypes DD, ID and II. ② The polymorphic information content of the BMP4 gene was 0.371, and was moderate polymorphism in the population（0.25≤PIC<0.50）; the polymorphic information content of the Krt85-1 gene locus was 0.337, and was moderate polymorphism in the population（0.25≤PIC<0.50）; the polymorphic information content of the Krt85-2 gene locus was 0.375, and was moderate polymorphism in the population（0.25≤PIC<0.50）; The polymorphic information content of the PPARGC1A gene was 0.294, and was moderate polymorphism in the population（0.25≤PIC<0.50）. ③ In terms of cooking loss, the ID genotype of BMP4 gene was significantly lower than that of DD genotype (P<0.05). In terms of shear force, the DD genotype of PPARGC1A gene was significantly lower than that of ID and II (P<0.05). In terms of color, the II genotype of the Krt85-1 gene locus was significantly lower than the DD and ID genotypes (P<0.05). For crude fat, the ID genotype at the Krt85-2 locus was significantly lower than that of genotype II (P<0.05). In conclusion, the BMP4, Krt85, and PPARGC1A genes could all be used as candidate genes for improving the meat quality of Small Tail Han sheep.

Key words: Small Tail Han sheep, BMP4 gene, Krt85 gene, PPARGC1A gene, polymorphism, meat quality

CLC Number:

S826.8

XU Tie-shan, DU Qiu-ming, HAN Zhi-song, HAO Xiao-ping, CHEN Jian, BAI Jun-yan. Association analysis between BMP4, Krt85, and PPARGC1A gene polymorphism and meat quality traits in Small Tail Han sheep[J]. HUBEI AGRICULTURAL SCIENCES, 2026, 65(2): 162-166.

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