党参硒多糖的获取、结构特征及生物活性研究进展

doi:10.14088/j.cnki.issn0439-8114.2025.09.023

摘要/Abstract

摘要： 总结了党参(Codonopsis pilosula)硒多糖的获取方法,包括党参生物转化法和化学合成法。党参生物转化法更适用于党参药材的农业生产;在化学合成法中,采用硝酸-亚硒酸钠法并辅以微波技术可显著提高硒化效率,更适合工业化生产。综述了党参硒多糖的化学成分、理化性质、结构表征等结构特征,以及抗氧化、抗肿瘤、免疫调节等生物活性的研究进展,并提出未来研究可从以下方面展开：深入优化制备工艺、建立质量控制标准与评价体系、拓展生物活性研究的广度、加强产品开发力度。

关键词: 党参(Codonopsis pilosula), 硒, 多糖, 结构分析, 生物活性, 补硒剂

Abstract: The acquisition methods of selenized Codonopsis pilosula polysaccharides were summarized, including the biological conversion method and the chemical synthesis method. The biological conversion method was more suitable for the agricultural production of Codonopsis pilosula medicinal materials. In the chemical synthesis method, the nitric acid-sodium selenite approach assisted by microwave technology significantly improved selenization efficiency and was more suitable for industrial production. This review covered the structural characteristics of selenized Codonopsis pilosula polysaccharides,such as chemical composition, physicochemical properties, and structural characterization,as well as advances in the study of their biological activities, including antioxidant, antitumor, and immunomodulatory effects. It was suggested that future research should focus on optimizing preparation processes, establishing quality control standards and evaluation systems, broadening the scope of biological activity studies, and enhancing product development efforts.

Key words: Codonopsis pilosula, selenium, polysaccharide, structural analysis, biological activity, selenium supplement

中图分类号:

胡平, 康振兴. 党参硒多糖的获取、结构特征及生物活性研究进展[J]. 湖北农业科学, 2025, 64(9): 141-147.

HU Ping, KANG Zhen-xing. Research progress on obtainment, structural characteristics and biological activity of selenizing Codonopsis pilosula polysaccharide[J]. HUBEI AGRICULTURAL SCIENCES, 2025, 64(9): 141-147.

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