湖北农业科学 ›› 2019, Vol. 58 ›› Issue (10): 125-128.doi: 10.14088/j.cnki.issn0439-8114.2019.10.029

• 贮藏·加工 • 上一篇    下一篇

酸枣叶总黄酮对小鼠体内抗氧化能力的影响

叶嘉1,2, 张浩1,2, 杨明建1,2, 付伟1,2   

  1. 1.邯郸学院生命科学与工程学院,河北 邯郸 056005;
    2.河北省高校冀南太行山区野生资源植物应用技术研发中心,河北 邯郸 056005
  • 收稿日期:2019-02-18 出版日期:2019-05-25 发布日期:2019-12-03
  • 通讯作者: 张浩(1983-),男,副教授,硕士,主要从事植物资源学研究,(电话)13503301605(电子信箱)zhanghao_55@163.com。
  • 作者简介:叶嘉(1963-),女,上海人,硕士,主要从事资源植物开发利用研究,(电子信箱)yejia630819@126.com。
  • 基金资助:
    河北省科技计划项目(18226435); 邯郸市科学技术研究与发展计划项目(1727201061-2); 河北省高等学校科学技术研究项目(ZD2017302); 邯郸学院校级科研资助项目(2017203; 15105; 2018104)

Antioxidant function in vivo of mice with flavonoids extracts from Ziziphus jujuba var. spinosa

YE Jia1,2, ZHANG Hao1,2, YANG Ming-jian1,2, FU Wei1,2   

  1. 1.School of Life Science and Engineering,Handan University,Handan 056005, Hebei,China;
    2.Research Center for Wild Plant Resources Applied Technology in Ji’Nan Mountain at University of Hebei Province,Handan 056005,Hebei,China;
  • Received:2019-02-18 Online:2019-05-25 Published:2019-12-03

摘要: 通过向小鼠灌胃不同剂量的酸枣叶(Ziziphus jujube var. spinosa)总黄酮[高剂量组300 mg/(kg·d);中剂量组150 mg/(kg·d);低剂量组100 mg/(kg·d)],测定小鼠体内总蛋白含量(TP)、过氧化物酶(POD)活性、超氧化物歧化酶(SOD)活性和过氧化氢酶(CAT)活性及总抗氧化活性(T-AOC),探讨酸枣叶总黄酮对小鼠体内抗氧化能力的影响。结果表明,灌施不同剂量的酸枣叶总黄酮对小鼠体内的TP浓度、POD、SOD、CAT及T-AOC活性产生了显著的影响(P<0.05)。随着添加剂量的增加,小鼠体内TP浓度、T-AOC和SOD活性呈逐渐升高的趋势,而POD活性呈先升高后下降的趋势,CAT活性随着剂量的增加无显著变化,但胃施酸枣叶总黄酮各处理小鼠体内酶活性均明显高于对照,说明酸枣叶总黄酮具有明显的抗自由基作用及体内抗氧化功能。

关键词: 酸枣叶(Ziziphus jujube var. spinosa), 抗氧化能力, 超氧化物歧化酶, 黄酮

Abstract: To examine antioxidant function in vivo of mice with flavonoids extracts from Ziziphus jujuba var. spinosa, the mice were gavaged with different doses of leaf avonoids[300 mg/(kg·d),150 mg/(kg·d),100 mg/(kg·d)]. The contents of TP,POD,SOD,CAT and T-AOC of the mice were assessed. The results showed that TP、POD、SOD、CAT and T-AOC were substantially affected by flavonoids extracts from Ziziphus jujuba var. spinosaP<0.01). The TP, T-AOC and SOD was increased with increasing of flavonoids extracts concentrations while the POD featured a bell-shape curve. There was no significant difference of CAT in the mice gavaged with different doses of leaf avonoids. Compared with normal control group,the TP, POD,SOD,CAT and T-AOC were increased significantly. The results showed that the flavonoids extracts from Ziziphus jujube var. spinosa can effectively improve the antioxidant function of mice.

Key words: Ziziphus jujube var. spinosa, antioxidant capacity, superoxide dismutase, avonoids

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