湖北农业科学 ›› 2020, Vol. 59 ›› Issue (7): 174-179.doi: 10.14088/j.cnki.issn0439-8114.2020.07.035

• 贮藏·加工 • 上一篇    下一篇

薏仁多糖的提取工艺优化及其抗氧化与透皮吸收作用

李树萍1, 彭俊超1, 李萌1, 安全2, 王昌涛1, 赵丹1   

  1. 1.北京工商大学理学院植物资源研究与开发重点实验室,北京100083;
    2.云南白药集团股份有限公司,昆明650504
  • 收稿日期:2019-09-02 发布日期:2020-06-28
  • 通讯作者: 李萌,女,副教授,(电子信箱)limeng@btbu.edu.cn。
  • 作者简介:李树萍(1991-),女, 河南驻马店人,在读硕士研究生,主要从事化妆品功效原料研究,(电话)15321324586(电子信箱)shupinglee@126.com;
  • 基金资助:
    云南省生物医药重大科技专项(2018ZF005)

Optimization of extraction conditions of coix polysaccharide and its inoxidizability and transdermal absorption

LI Shu-ping1, PENG Jun-chao1, LI Meng1, AN Quan2, WANG Chang-tao1, ZHAO Dan1   

  1. 1. Key Laboratory of Plant Resources Research and Development, School of Science, Beijing Technology and Business University, Beijing 100083, China;
    2. Yun Nan Bai Yao Co.,Ltd, Kunming 650504, China
  • Received:2019-09-02 Published:2020-06-28

摘要: 对薏仁多糖的水提和发酵的提取条件进行了优化,并研究了薏仁多糖提取液抗氧化活性和透皮吸收效果。结果表明,薏仁多糖水提的最佳条件为料液比0.11(g/mL),温度90 ℃,时间7 h;发酵最佳条件为酿酒酵母,料液比0.1(g/mL),时间54 h,pH 4.5;薏仁多糖发酵提取率约为水提的3倍。薏仁多糖发酵液抗氧化性优于水提液;薏仁多糖发酵液24 h透过率为1.14 mg/cm2,水提液24 h透过率为0.53 mg/cm2

关键词: 薏仁多糖, 水提, 发酵, 抗氧化, 透皮吸收

Abstract: To optimize the extraction and fermentation conditions of the polysaccharide of Coix kernel And studied its antioxidation and transdermal absorption effect, which provided reference for its application in anti-aging and transdermal absorption of human body. Results showed that the optimum conditions for the water extraction of Coix polysaccharide were 0.11, the temperature was 90 ℃, the time was 7; the best fermentation condition was Saccharomyces cerevisiae, the material liquid was 0.1, the time 54h,PH was 4.5; the extraction rate of coix polysaccharide was about 3 times of water. The antioxidant resistance of coix polysaccharide fermentation broth is better than that of water extract. The 24 h transmittance of coix polysaccharide fermentation broth was 1.14 mg/cm2, and the 24h transmittance of water extract was 0.53 mg/cm2.

Key words: coix polysaccharide, water extraction, fermentation, antioxidation, transdermal absorption

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