Abstract: UV spectrophotometry was used to determine total saponins of Phytolacca americana by the sulphuric acid vanillin colorimetric method,HPLC-UV Method was used to determine the content of esculentoside A. Results showed that their contents of the group dry in the shade were Significantly lower than the other groups,the group dry in the sun were the second from the bottom,the group dry hot air were higher. Among them, the content of total saponin of Phytolacca americana was the highest dry at 55 ℃, and the content of esculentoside A was the highest dry at 80 ℃. It should be dried in time, avoiding the loss of ingredients, drying in large scale is better than traditional drying, and drying at low temperature is advisable.

Key words: Phytolacca americana, producing processing, drying method, total saponins, esculentoside A