Effect of feeding Gynostemma Pentaphyllum on the thymus aging of Guangxi Sanhuang chickens

doi:10.14088/j.cnki.issn0439-8114.2020.03.023

Abstract

Abstract: From the histological point of view, the effect of adding Gynostemma pentaphyllum on the thymus aging of Guangxi Sanhuang chickens was studied. 0.5% G. pentaphyllum powder was added to the feed, and the thymus weight, thymus index, cortex-medium area ratio, number and area of thymus bodies were examined at 1, 14, 28, 56, 90, 120, and 150 d. The results showed that with increasing age, the thymus weight increased, and the thymus index rose first and then decreased. The addition of G. pentaphyllum increased the thymus weight and thymus index to a certain extent. With the increase of the age, the thymic cortex-medullar ratio decreased, and at 120 d, the cortex-medullar ratio of the fed group was significantly greater than that of the non-added group（P<0.05）. The number of thymus bodies in the non-feeding group and the feeding group increased before 56 and 90 d, respectively, and then decreased in a wave pattern. At 28, 90, and 120 d, the number of thymus bodies in the fed group was significantly more than that in the non-fed group（P<0.05）. The thymus body area of the non-feeding group and the feeding group increased before 120 d, and then decreased. The day-to-day differences of the non-feeding group and the feeding group were not significant. Adding G. pentaphyllum powder in the feed can prolong the thymus maturation time, delay the thymus degradation, and improve the thymus function.

Key words: Gynostemma pentaphyllum, Guangxi Sanhuang chicken, thymus, ageing

CLC Number:

S831
R285.5

ZHANG Run-xiang, WU Ya-hui, HUANG Shi-qi, WANG Yong-jie, BAI Xi, TANG Xiao-chuan, WANG Xiao-li. Effect of feeding Gynostemma Pentaphyllum on the thymus aging of Guangxi Sanhuang chickens[J]. HUBEI AGRICULTURAL SCIENCES, 2020, 59(3): 111-114.

References

[1] 张彤,刘为鹏,李华,等.中国绞股蓝种质资源的生态分布及利用[J].陕西农业科学,2015,61(4): 55-59.
[2] XU J Q,SHEN Q,LI J,et al.Dammaranes from Gynostemm apentaphyllum and synthesis of their derivatives as inhibitors of protein tyrosine phosphatase 1B[J].Bioorg Med Chem,2010, 18(11):3934-3939.
[3] 伍国怡. 药用植物绞股蓝的研究进展[J].中国民族民间医药,2016,25(12):60-63.
[4] YU Y,WANG D Q,ABULA S,et al.The immunological adjuvant activity of gypenosides liposome against newcastle disease vaccine[J].International journal of biological macromolecules,2013, 60(9):116-121.
[5] 任小杰. 银杏叶及其提取物对肉鸡生产性能、抗氧化指标和免疫性能的影响[D].山东泰安:山东农业大学,2018.
[6] 严晓丹,姜成.八味方对小鼠免疫功能的影响[J].海峡药学,2008,20(9):34-35.
[7] 张海燕,郭强,温伟业.绞股蓝总皂苷对小鼠免疫功能的影响[J].中兽医学杂志,2006(2):13-15.
[8] 王云. 鸡胸腺发育形态学研究[D].武汉:华中农业大学,2010.
[9] 陈敏,黄立,肖柯,等.非洲雏鸵鸟胸腺发育的增龄性变化[J].中国兽医学报,2014,34(6):955-958.
[10] 刘仰斌,李启华.小鼠胸腺形态结构的增龄性变化[J].中国组织工程研究与临床康复,2010,14(31):5805-5808.
[11] 金光明,张敏,汤苏丽.半胱胺对鸡免疫器官组织结构及发育的影响[J].畜牧与饲料科学,2009,30(3):9-11.
[12] 冉瑞图,孙嘉政,张晶,等.人参皂苷Rg1对衰老大鼠胸腺结构与功能的影响[J].中国老年学杂志,2015,35(10):2593-2596.
[13] 方静,崔恒敏,彭西,等.雏鸭胸腺生长指标的动态观测及组织学观察[J].中国兽医科学,2006,36(5):401-405.
[14] 张倩. 不同年龄段牦牛胸腺的组织结构特征[D].兰州:甘肃农业大学,2013.
[15] 关莉,黄中新.胸腺小体在胸腺发育中的形态发生及其功能探讨[J].广东解剖学通报,1997,19(1):4-6.
[16] ZAPATA A G,COOPER E L.The immune system:Comparative histophysiology[M].Michester:John Wiley & Sona,1991.
[17] 张勇. 蛋鸡和肉鸡生长发育过程中胸腺组织结构、T细胞及其亚群分布的研究[D].呼和浩特:内蒙古农业大学,2009.
[18] 殷中琼,喻印,贾仁勇,等.青刺果种粕粉对鸡免疫器官发育的影响[J].动物营养学报,2007,19(3):245-252.
[19] 王群,王珏.松针粉-麦饭石复合添加剂对肉鸡胸腺生长发育的影响[J].饲料工业,2005,26(16):42-44.