Polymorphism of porcine OLR1 gene and its association with liter size trait of Xidu black pigs

doi:10.14088/j.cnki.issn0439-8114.2020.24.032

HUBEI AGRICULTURAL SCIENCES ›› 2020, Vol. 59 ›› Issue (24): 141-143.doi: 10.14088/j.cnki.issn0439-8114.2020.24.032

• Animal Husbandry & Veterinary Medicine • Previous Articles Next Articles

Polymorphism of porcine OLR1 gene and its association with liter size trait of Xidu black pigs

QIAO Mu, LI Kang-chi, WU Jun-jing, WU Hua-yu, ZHOU Jia-wei, MEI Shu-qi, PENG Xian-wen

Huibei Key Laboratory of Animal Embryo and Molecular Breeding/Institute of Animal and Veterinary Science, Hubei Academy of Agricultural Sciences, Wuhan 430064, China

Received:2020-10-29 Online:2020-12-25 Published:2021-01-21

Abstract

Abstract: In order to explore the effect of OLR1 gene genetic polymorphism on litter size of Xidu black pigs, the direct sequencing method was used to detect the genetic polymorphism of OLR1 gene in the Xidu black pigs, and the association analysis with litter size was carried out. The results showed that there was a T/C mutation at 7 bp of intron 4, and there were three genotypes TT, TC and CC; The total number born and number born alive of individuals with TT genotype were extremely significantly higher than those with TC and CC genotype (P<0.01), indicating that the mutation had a significant impact on litter size traits of Xidu black pig.

Key words: OLR1 gene, Xidu black pig, litter size, association analysis

CLC Number:

S828

QIAO Mu, LI Kang-chi, WU Jun-jing, WU Hua-yu, ZHOU Jia-wei, MEI Shu-qi, PENG Xian-wen. Polymorphism of porcine OLR1 gene and its association with liter size trait of Xidu black pigs[J]. HUBEI AGRICULTURAL SCIENCES, 2020, 59(24): 141-143.

References

[1] KATAOKA H, KUME N, MIYAMOTO S, et al.Oxidized LDL modulates Bax/Bcl-2 through the lectinlike Ox-LDL receptor-1 in vascular smooth muscle cells[J]. Arteriosclerosis, thrombosis, and vascular biology,2001,21:955-960.
[2] LIU X, ZHU R X, LI L, et al.Association of LOX-1 gene polymorphisms with cerebral infarction in northern Chinese Han population[J]. Lipids Health Dis, 2014,13(55):1-6.
[3] KELISHADI R, NADERY G A, ASGARY S.Oxidized LDL metabolites with high family risk for premature cardiovas-cular disease[J]. Indian J Pediatr, 2002, 69(9):755-759.
[4] PIRILLO A,CATAPANO A L.Soluble lectin-like oxidized low density lipoprotein receptor-1 as a biochemical marker for atherosclerosis-related diseases[J]. Disease markers,2013, 35(5):413-418.
[5] PATRICIA C,GUAN H P,MICHAEL L.PPARγ regulates adipocyte cholesterol metabolism via oxidized LDL receptorl[J]. Clin Invest, 2005, 115(8):2244-2256.
[6] JUWON A, MATTHEW K, FRANKLIN, et al. Linoleic acid regulates the expression of oxidized low density lipoprotein receptor (OLR1) in 3T3-L1 adipocytes via ERK and JNK pathways[J]. FASEB journal, 2007, 21(5): A455 APR.
[7] 孙超, 刘春伟. 脂肪酸对小鼠前体脂肪细胞增殖分化及OLR1基因转录表达的作用[J].西北农林科技大学学报, 2009, 37(3): 1-6.
[8] 郭咪咪,乔木,吴俊静,等.猪OLR1基因克隆及其与生产性状的关联、表达分析[J].华中农业大学学报(自然科学版),2015,34(3):82-88.
[9] 郭咪咪,梅书棋,乔木,等.猪OLR1基因多态性与肉质性状的关联分析[J].湖北农业科学,2015,54(11):2686-2689.
[10] ZHANG X, HUANG L, WU T, et al. Transcriptomic analysis of ovaries from pigs with high and low litter size[J]. Plos one,2015,10(10):eo139514.
[11] 王万兴, 张琪, 张树敏. 松辽黑猪RBP4基因多态性及其与繁殖性状的关联分析[J]. 中国畜牧兽医, 2020, 47(8): 2493-2501.
[12] 李志勋, 富国文, 信吉阁, 等. 保山猪PRLR, NOCA1和HTRA3基因多态性与其产仔数的关联分析[J]. 畜牧与兽医, 2020(4):19-23.
[13] 甘乾福, 孟洪莉, 乔慧, 等.OPN基因多态性与猪繁殖性状相关分析[J]. 福建农林大学学报(自然科学版), 2012,41(3):266-270.
[14] 林鹏飞,任丽群,李平,等.宗地花猪BMPR1B基因多态性与繁殖性状的关联性[J]. 江苏农业科学, 2017,45(17):35-38.
[15] 周梅, 张玉, 王重龙. 猪产仔数性状候选基因研究进展[J]. 家畜生态学报, 2020(8):1-6.

Polymorphism of porcine OLR1 gene and its association with liter size trait of Xidu black pigs

PDF

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 5

Recommended Articles

Metrics

Comments

[1]	QIAO Tong-tong, ZHANG Yu, LI Zi-peng, QIAO Mu, QIN Zhen-yang, PENG Xian-wen, WU Jun-jing. Association analysis of NARS2 gene variation and carcass and meat quality traits in selenium black pig [J]. HUBEI AGRICULTURAL SCIENCES, 2023, 62(12): 195-199.
[2]	WU Jun-jing, DONG Bin-ke, QIAO Mu, MEI Shu-qi, PENG Xian-wen. Identification of the mutations in porcine MMP20 gene and its association analysis with reproduction traits [J]. HUBEI AGRICULTURAL SCIENCES, 2020, 59(21): 110-112.
[3]	ZHOU Jia-wei, QIAO Mu, WU Jun-jing, WANG Xiao-zhong, LIU Gui-sheng, MEI Shu-qi, PENG Xian-wen. Association analysis of polymorphism of pig DKK2 gene and sow litter size traits [J]. HUBEI AGRICULTURAL SCIENCES, 2020, 59(20): 138-140.
[4]	XIONG Qi, CHEN Wen-juan, PENG Jian, CHAI Jin, LIU Yang, CHEN Ming-xin, YANG Jun, YANG Feng, JIANG Si-wen. Elucidating the relationship between MC4R,NR6A1 gene and economic traits of black pigs in Yorkshire×Qingping F₂ breed [J]. HUBEI AGRICULTURAL SCIENCES, 2019, 58(5): 88-91.
[5]	LI Xiao-mei, ZHANG Jing-tao. Association analysis of genetic diversity and traits in Coriander [J]. HUBEI AGRICULTURAL SCIENCES, 2019, 58(21): 107-112.