HUBEI AGRICULTURAL SCIENCES ›› 2024, Vol. 63 ›› Issue (6): 141-150.doi: 10.14088/j.cnki.issn0439-8114.2024.06.023

• Animal Husbandry & Veterinary Medicine • Previous Articles     Next Articles

The therapeutic effect of phycocyanin on skin damage in mice

SHAO Li-lin, XIE You-yin, ZHANG Lei-fang   

  1. School of Food and Pharmacy, Zhejiang Ocean University/Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products , Zhoushan 316022, Zhejiang, China
  • Received:2022-11-05 Online:2024-06-25 Published:2024-06-26

Abstract: To investigate the therapeutic effect of C-phycocyanin (CPC) on skin injuries in mice, ICR mice were divided into five groups: normal control group (Con), model group (Mod), blank dressing group (BD), CPC-treated dressing group (CPC TDD), and CPC-treated dressing plus intraperitoneal injection of CPC group (CPC+ip.) for conducting mouse scalding experiments. The results showed that the wound healing time was the shortest in the CPC TDD and CPC+ip. groups, which could reduce the content of malondialdehyde (MDA) in serum, increase the content of superoxide dismutase (SOD), and decrease levels of inflammatory factors TNF-α and IL-6 in serum. Phycocyanin could promote skin injury healing by enhancing antioxidant capacity and reducing levels of inflammatory factors.

Key words: C-phycocyanin, mice, skin injury, wound healing, scalding, seawater immersion

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