Research progress on obtainment, structural characteristics and biological activity of selenizing Codonopsis pilosula polysaccharide

doi:10.14088/j.cnki.issn0439-8114.2025.09.023

Abstract

Abstract: The acquisition methods of selenized Codonopsis pilosula polysaccharides were summarized, including the biological conversion method and the chemical synthesis method. The biological conversion method was more suitable for the agricultural production of Codonopsis pilosula medicinal materials. In the chemical synthesis method, the nitric acid-sodium selenite approach assisted by microwave technology significantly improved selenization efficiency and was more suitable for industrial production. This review covered the structural characteristics of selenized Codonopsis pilosula polysaccharides,such as chemical composition, physicochemical properties, and structural characterization,as well as advances in the study of their biological activities, including antioxidant, antitumor, and immunomodulatory effects. It was suggested that future research should focus on optimizing preparation processes, establishing quality control standards and evaluation systems, broadening the scope of biological activity studies, and enhancing product development efforts.

Key words: Codonopsis pilosula, selenium, polysaccharide, structural analysis, biological activity, selenium supplement

CLC Number:

HU Ping, KANG Zhen-xing. Research progress on obtainment, structural characteristics and biological activity of selenizing Codonopsis pilosula polysaccharide[J]. HUBEI AGRICULTURAL SCIENCES, 2025, 64(9): 141-147.

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