Study on Microwave Extracting and Antitumor Activity of Total Saponins from H.emerocallisfulva

doi:10.14088/j.cnki.issn0439-8114.2018.21.023

HUBEI AGRICULTURAL SCIENCES ›› 2018, Vol. 57 ›› Issue (21): 93-96.doi: 10.14088/j.cnki.issn0439-8114.2018.21.023

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Study on Microwave Extracting and Antitumor Activity of Total Saponins from H.emerocallisfulva

LIU Li-xin^a, ZHANG Xue-song^b, ZHANG Yu-nan^a, YE Zhi-hui^c, SUN Jing^b, YU Hai-tao^b, LI Jing^d, WANG Jing^b, LUO Wen-ze^d, ZHANG Qiang^e

a.School of Pharmacological Sciences;
b.First Affiliated Hospital;
c.Department of Stomatology,First Affiliated Hospital;
d.School of Basic Medical Sciences;
e.School of Public Health,Jiamusi University,Jiamusi 154007,Heilongjiang,China

Received:2018-04-27 Online:2018-11-10 Published:2020-01-13

Abstract

Abstract: Using microwave power, extracted time and solid-liquid ratio as main factors, the L₉（3³） orthogonal design was used for optimizing the extraction conditions of total saponins from H.emerocallisfulva. The optimum conditions were as：microwave power at 420 W,45 s of extracted time and solid-liquid ratio at 1∶50（g∶mL）. Antitumor activity of total saponins from H.emerocallisfulva was studied by the SRB assay,the result shows that total saponins from H.emerocallisfulva demonstrated good antitumor activity on human hepatoma HepG2 cells,and better than the ginsenosides Rb1.

Key words: H.emerocallisfulva, total saponins, microwave extraction, antitumor activity

CLC Number:

R284.2

LIU Li-xin, ZHANG Xue-song, ZHANG Yu-nan, YE Zhi-hui, SUN Jing, YU Hai-tao, LI Jing, WANG Jing, LUO Wen-ze, ZHANG Qiang. Study on Microwave Extracting and Antitumor Activity of Total Saponins from H.emerocallisfulva[J]. HUBEI AGRICULTURAL SCIENCES, 2018, 57(21): 93-96.

References 10

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Study on Microwave Extracting and Antitumor Activity of Total Saponins from H.emerocallisfulva

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