Abstract: Headspace solid phase microextraction （HS-SPME） combined with gas chromatography-mass spectrometry （GC-MS） was used to analyze the volatile components of Guizhi Fuling bolus,Guizhi Fuling tablets and Guizhi Fuling capsules, the relative contents of each component were calculated. The results showed that 22 peaks were detected from Guizhi Fuling bolus, 17 components were identified, accounting for 98.41% of the volatile components, 15 peaks were detected from Guizhi Fuling tablets, 12 components were identified, accounting for 89.12% of the volatile components, and 30 peaks were identified from Guizhi Fuling capsules, accounting for 99.46% of the volatile components. The composition and content of volatile components in Guizhi Fuling bolus and other dosage forms changed.

Key words: Guizhi Fuling bolus, Guizhi Fuling tablets, Guizhi Fuling capsules, HS-SPME, GC-MS, volatile components