Zyxin protein function in cells and its research progress

doi:10.14088/j.cnki.issn0439-8114.2020.04.003

Abstract

Abstract: Zyxin protein is an important member of the focal adhesion protein complex, which is a highly dynamic multiprotein complex found in cells. It is capable of transmitting signals from the extracellular matrix to the nucleus. Zyxin protein has a broad proline-rich domain, a nuclear export signal and three copies of the LIM motif. Recent studies have shown that Zyxin protein not only functions in actin-related biological processes, but also plays an important role in cell migration, cell adhesion, cell growth, DNA damage repair, tumor growth, and natural immunity. The function of Zyxin protein mainly in cells and the latest research progress was described.

Key words: Zyxin protein, DNA damage repair, actin regulation, immunity, tumor

CLC Number:

YUE Shi-chao, CAO Ya-qian. Zyxin protein function in cells and its research progress[J]. HUBEI AGRICULTURAL SCIENCES, 2020, 59(4): 13-17.

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