Abstract: The volatile components of folium isatidis and radix isatidis were analyzed and compared by headspace solid phase microextraction （HS-SPME） combined with GC-MS. The relative percentage of each component was calculated by area normalization method. Results showed that 38 peaks were isolated from folium isatidis and 31 components were identified, accounting for 81.58% of the volatile components. 35 peaks were isolated from radix isatidis and 28 components were identified, accounting for 80.00% of the volatile components. There are 16 kinds of volatile components in the two, which account for 48.16% and 48.40% of the total volatile components of folium isatidis and radix isatidis, respectively. There were some differences in the volatile components and content of folium isatidis and radix isatidis, and they have some of the same pharmacological effects.

Key words: folium isatidis, radix isatidis, HS-SPME-GC-MS, volatile components