Isolation and anti-monoamine oxidase activity of endophytic fungi from four medicinal plants

doi:10.14088/j.cnki.issn0439-8114.2021.03.010

Abstract

Abstract: Endophytic fungi were isolated and identified from the roots and stems of four medicinal plants, Euphorbia pulcherrima,Salvia przewalskii, Acanthopanax senticosus and Hypericum ascyron. The anti-monoamine enzyme activity of ethyl acetate extract of fermentation product from these endophytes was screened, and chemical constituents from these endophytes were isolated by column chromatography and spectroscopy methods. The results showed that 20 endophytic fungi strains were obtained. Among them, the inhibition rate of anti-monoamine oxidase activity of SJ-2, WJ-3, HJ-1 was 83.8%, 84.2%, 71.9%, respectively. According to the colony characteristics and morphological characteristics, the endophytic fungus SJ-2 was identified as Fusarium sp., WJ-3 was identified as Penicillium sp., and HJ-1 was identified as Alternaria sp.. Three compounds, Enniatin B, Monomethylsulochrin, Fumitremorgin C were isolated from strain SJ-2.

Key words: medicinal plants, endophytic fungi, secondary metabolites, biological activity, monoamine oxidase inhibitor

CLC Number:

GOU Wen-bo, YANG Zhong-duo, ZHOU Ge-ge. Isolation and anti-monoamine oxidase activity of endophytic fungi from four medicinal plants[J]. HUBEI AGRICULTURAL SCIENCES, 2021, 60(3): 56-59.

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