HUBEI AGRICULTURAL SCIENCES ›› 2021, Vol. 60 ›› Issue (24): 164-168.doi: 10.14088/j.cnki.issn0439-8114.2021.24.036

• Animal Husbandry & Veterinary Medicine • Previous Articles     Next Articles

Study on the application of fermented Chinese medicine preparation to replace antibiotics in broiler diet

WANG Dan, CUI Wei-tao, WANG Chun, KUANG Shi-chang, XU Qing-rong, XIAO Yun-cai, LI Zi-li, ZHOU Zu-tao   

  1. College of Veterinary Medicine,Huazhong Agricultural University/Hubei Key Laboratory of Preventive Veterinary Medicine/Hubei Engineering Research Center of Biofermentation Feed,Wuhan 430070,China
  • Received:2021-08-19 Online:2021-12-25 Published:2022-01-04

Abstract: The purpose of this study is to evaluate the effects of fermented Chinese medicine (FCM) on broiler production performance, serum antioxidant index, immune function, intestinal morphology and caecum flora, and provide technical support for the application of FCM preparation in broiler production. A total of 288 1-day-old AA broilers were randomly divided into 3 groups, the control group was fed with basal diet, the antibiotic group was fed with basal diet containing 50 g/t chlortetracycline, and the FCM preparation group was fed with basal diet supplemented with 3 kg/t probiotic FCM preparation. The experimental period was 42 days. The results showed that the output weight of FCM preparation group was higher than that of control group and test group. Compared with the control group and the experimental group, the average daily gain of FCM group was increased by 8.19% (P<0.05) and 4.61% (P<0.05), respectively. The feed to meat ratio was significantly decreased by 0.02 (P>0.05) compared with the antibiotic group. The serum antioxidant index was improved by FCM preparation. Compared with the antibiotic group, the thymus index of the FCM group increased by 61.96% (P<0.05), and serum IL-1β, the content of endotoxin decreased by 28.73% (P<0.05) and 23.36% (P<0.05), and the content of IL-6 and IL-10 increased by 117.63% P<0.05) and 36.85% (P>0.05), respectively. Compared with the control group and antibiotic group, the sIgA content of ileum and cecum in the FCM group increased by 44.2% (P<0.05) and 66.9% (P<0.05) respectively, and 43.4% (P<0.05) and 65.5% (P<0.05) respectively. Compared with the control group and antibiotic group, the VH/VD values of ileum and cecum in the FCM preparation group were significantly increased. Compared with the control group and antibiotic group, the content of Lactobacillus in the FCM preparation group was the highest, increased by 40.66% and 24.27% (P<0.05), the number of Faecalis prussii increased by 12.44% and 3.42% (P<0.05), and the content of Salmonella decreased by 17.76% and 20.96% (P<0.05). The FCM preparation had good probiotic function, which could improve the disease resistance, regulate the intestinal morphology and beneficial flora, and promote the production performance.

Key words: fermented Chinese medicine preparation, antibiotics, broilers, production performance, immunity, flora

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