Effects of valerenic acid on the blood and intestinal microbiota of calves

doi:10.14088/j.cnki.issn0439-8114.2025.03.019

Abstract

Abstract: In order to study the effects of valerenic acid on body weight, blood physiological and biochemical indexes and intestinal microbiota of calves, healthy calves were selected and divided into 0.8% valerenic acid Chinese medicine group and control group, with 10 calves in each group, and fed for 2 months. The results showed that feeding 0.8% valerenic acid had no significant difference in body weight and blood physiological indexes of calves, decreased serum albumin content, significantly increased intestinal bacteroidetes content, and significantly increased the abundance of bacteroidetes, which could play a role through intestinal microbiota.

Key words: Valeriana officinalis L., valerenic acid, blood physiology, serum biochemistry, microorganisms

CLC Number:

S823

JIANG Ling-ling, RAN Jiang, LUO Wen-ju, ZHOU Jing-rui, WANG Xin, YU Bo. Effects of valerenic acid on the blood and intestinal microbiota of calves[J]. HUBEI AGRICULTURAL SCIENCES, 2025, 64(3): 118-121.

References

[1] 万之瑜,蒋珞晨,姜付平. 近十年SCIE收录的缬草论文统计分析[J]. 亚太传统医药,2023,19(1):174-177.
[2] 王昊冉,盛可心,代威,等. 缬草的药理作用及其机制研究进展[J]. 中药材,2022,45(12):3025-3030.
[3] 但林蔚,高天慧,吴国庆,等. 缬草的化学成分研究[J].中南药学,2023,21(9):2300-2306.
[4] 魏桂民,李德文,王少铭,等. 缬草研究进展[J]. 农技服务,2016,33(12):18-19.
[5] 李文杰,李美阳. 药用植物缬草的研究进展[J]. 北方园艺,2019(12):139-145.
[6] 樊浩,严淑婷,梁小飞,等. 缬草化学成分及生理活性研究进展[J]. 辽宁中医药大学学报,2019,21(12):172-175.
[7] 姜翠霞. 西北主要中药材对泌乳牦牛和犊牛营养及生理代谢的影响[D]. 兰州:兰州大学,2021.
[8] 周景瑞,姜玲玲,雷露,等. 不同年份缬草精油挥发性成分的差异分析[J]. 湖北农业科学,2023,62(5):160-164.
[9] 聂鲜钰. 不同栽培措施对宽叶缬草挥发油成分的影响[D]. 贵州:贵州大学,2020.
[10] 刘抒雯. 中药单体缬草烯酸协载dCas9 VP64 mRNA及其sgRNA纳米粒对阿尔茨海默病作用机制的研究[D]. 长春:长春中医药大学,2019.
[11] ZHANG X R,ZUO Z Z,LIU Y,et al.Effect of methionine analogues on growth performance, serum biochemical parameters,serum free amino acids and rumen fermentationofyaks[J]. Animals,2022,12(22):3175.
[12] 张建刚,李文婷,庄涛,等.玉米秸秆青贮与稻草的不同比例对肉羊生长性能和血液生化指标的影响[J]. 广东饲料,2012,21(6):23-26.
[13] 施安,王建东,孙文阳,等. 宁夏地区育肥牛舍温湿度对安格斯牛血清指标的影响[J]. 中国饲料,2024(5):160-165.
[14] BRSCIC M,COZZIG,LORAI,et al.Short communication:Reference limits for blood analytes in Holstein late pregnantheifers and dry cows: Effects of parity, days relative to cal-ving,and season[J]. Journal of dairy science,2015,98(11):7886-7892.
[15] 马毅,沈思军,潘晓亮,等. 不同月龄安格斯牛在冬夏两季血液生理与生化指标的比较[J].家畜生态学报,2020,41(2):40-44.
[16] 薛萌晓,王传龙,张卫云,等.饲粮添加不同形态锌对肉仔鸡血浆生化指标、抗氧化能力及免疫功能的影响[J].动物营养学报,2024,36(5):2982-2991.
[17] 吴茂,翁家俊,崔粲,等. 中药基于肠道菌群实现免疫调节的研究进展[J]. 中药材,2022,45(8):2009-2016.
[18] ZIELINSKA S, KIDAWA D, STEMPNIEWICZ L, et al.New insights into the microbiota of the Svalbard reindeer Rangifer tarandus platyrhynchus[J]. Front microbiol, 2016, 7:170.
[19] 王晨. 肠道拟杆菌种结构组成对溃疡性结肠炎发展的影响[D]. 江苏无锡:江南大学,2021.
[20] TIAN B, ZHAO J, ZHANG M, et al.Lycium ruthenicum anthocyanins attenuate high-fat diet-induced colonic barrier dysfunction and inflammation in mice by modulating the gut microbiota[J]. Molecular nutrition & food research, 2021, 65(8): e2000745.
[21] HE B B, LI T T, WANG W, et al.Metabolic characteristics and nutrient utilization in high feed efficiency pigs selected using different feed conversion ratio models[J]. Sci China Life Sci, 2019, 62(7): 959-970.