HUBEI AGRICULTURAL SCIENCES ›› 2018, Vol. 57 ›› Issue (24): 93-95.doi: 10.14088/j.cnki.issn0439-8114.2018.24.025

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Study on Antibacterial Active Components of Fungi SF_24818

WU Zhao-yuan, ZHANG Ya-ni, FANG Wei, SHI Li-qiao, LIU Man-li   

  1. Hubei Biopesticide Engineering Research Center,Wuhan 430064,China
  • Received:2018-05-25 Online:2018-12-25 Published:2020-04-01

Abstract: In the search for antimicrobial natural products, fungus SF_24818 with strong antimicrobial activity was obtained. By active tracking,the active fraction was detected,and two active compounds which were identified as neohydroxyaspergillic acid and aspergillic acid by UV,MS and NMR were isolated from the culture of large scare fermentation of SF_24818. Further antimicrobial activity tests showed that the two active compounds had significant antimicrobial effect to Staphylicoccus aureus.

Key words: antimicrobial activity, fungi, neohydroxyaspergillic acid, aspergillic acid

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