HUBEI AGRICULTURAL SCIENCES ›› 2021, Vol. 60 ›› Issue (11): 102-106.doi: 10.14088/j.cnki.issn0439-8114.2021.11.021

• Storage & Processing • Previous Articles     Next Articles

Optimization of extractions of Yigen Tiaoli paste by orthogonal design based on entropy weight method

JIANG Lin1,2, GUO Yong-xiu1, LI Fang-chan1,2, PANG Xiao-yun3, WEI Bo-wei1, SUI Jia-ning1   

  1. 1. School of Pharmacy, Guangxi University of Chinese Medicine,Nanning 530001,China;
    2. Guangxi Zhuang Yao Medicine Center of Engineering and Technology,Nanning 530001,China;
    3. Pharmaceutical Factory,Guangxi University of Chinese Medicine,Nanning 530001,China
  • Received:2020-07-23 Online:2021-06-10 Published:2021-07-15

Abstract: The contents of total flavonoids, psoralen and nootkatone were used as the indicators, the alcohol concentration and volune, extraction time, number of repeated extractions were used as the influencing factors. orthogonal design was used to optimize the alcohol extraction process of Yigen Tiaoli paste based on entropy weight method weighted evaluation. Determination of psoralen and nootkatone by high performance liquid chromatography and determination of total flavonoids by UV spectrophotometry. The results showed that the weight coefficients of total flavonoids, psoralen and nootkatone were 0.336 9, 0.335 1 and 0.328 0, respectively. Optimization of extraction was as follows: extractions 2 times with 70% ethanol, and each time with 12-fold ethanol volume and 1h extraction. The extraction process is stable, and can be used as the alcohol extraction.

Key words: Yigen Tiaoli paste, total flavonoids, psoralen, nootkatone, alcohol extraction

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