Abstract: Taking Evodia rutaecarpa as raw materials, and total flavonoids content as the index, on the basis of single factor experiment, the optimization of extraction of flavonoids from Evodia rutaecarpa was investigated by orthogonal experimental design. The optimum conditions were ethanol concentration at 70%, solid-liquid ration at 1∶50, extraction time at 40min and extraction temperature at 65℃. The results showed that the extracting rate of total flavonoids reached 8.82%. The antioxidant activity of flavonoids from Evodia rutaecarpa had good ability to scavenge DPPH· free radical.

Key words: Evodia rutaecarpa, total flavonoids, extract process, antioxidant activity